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柳叶红千层分离黄酮的成分及其生物活性研究(PDF)

《西南林业大学学报》[ISSN:2095-1914/CN:53-1218/S]

期数:
2017年04期
页码:
209-212
栏目:
出版日期:
2017-06-30

文章信息/Info

Title:
Flavones and Their Biological Activities from the Leaves of Callistemon salignus
文章编号:
2095-1914(2017)04-0209-04
作者:
李盼盼华燕王军民
西南林业大学林学院,云南 昆明 650224
Author(s):
Li Panpan Hua Yan Wang Junmin
College of Forestry, Southwest Forestry University, Kunming Yunnan 650224, China
关键词:
柳叶红千层黄酮抗菌活性抗氧化活性
Keywords:
Callistemon salignus leaves flavones antioxidant activity antibacterial activity
分类号:
S789
DOI:
10.11929/j.issn.2095-1914.2017.04.031
文献标识码:
A
摘要:
利用硅胶和葡聚糖凝胶柱层析方法对柳叶红千层叶中化学成分进行分离纯化并结合波谱数据和理化性质鉴定化合物的结构,同时测定其抗氧化和抗菌的活性。结果表明:从柳叶红千层叶中分离得到2个化合物,其结构鉴定为5-羟基-6, 8-二甲基-7, 4′-二甲氧基黄酮和5-羟基-6-甲基-7, 4′-二甲氧基黄酮。5-羟基-6-甲基-7, 4′-二甲氧基黄酮表现出较明显的抗氧化活性IC50值20.0 μg/mL,并表现出一定的抗菌活性,对大肠杆菌的MIC值为62.5 μg/mL。
Abstract:
The chemical constituents from Callistemon salignus were isolated and purified by silica gel and Sephadex LH-20 column chromatographies. Their structures were elucidated on the basis of spectral data and physicochemical property analyses. The antioxidant and antimicrobial activities of isolates were also evaluated. Two flavones were obtained from C.salignus and their structures were identified as 5-hydroxy-6, 8-dimethy-7, 4′-dimethoxy flavone and 5-hydroxy-6-methyl-7, 4′-dimethoxyflavone. Two known flavones were isolated from the leaves of C.salignus for the first time and 2 exhibited significant antioxidant with IC50=20.0 μg/mL, and the antibacterial activity against Escherichia coli (ATCC 25922) with MIC=62.5 μg/mL.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期:2017-03-03; 修回日期:2017-05-26
基金项目:云南省科技计划项目(2016FD045)资助。
第1作者:李盼盼(1991—),女,硕士生。研究方向:植物化学。Email: 15559865755@163.com
通信作者:王军民(1987—),男,硕士。研究方向:植物化学。Email: dawn723@163.com
更新日期/Last Update: